Knowledge Management System Of Guangzhou Institute of Energy Conversion, CAS
| Double-lipase Catalyzed Synthesis of Kojic Dipalmitate in Organic Solvents | |
Wang Zhiyuan; Luo Wen ; Fu Junying; Li Zhibing; Wang Zhongming; Lu Pengmei
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| 2017-12-01 | |
| Source Publication | CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
 |
| ISSN | 1005-9040 |
| Volume | 33Issue:6Pages:903-907 |
| Corresponding Author | Lu Pengmei(lvpm@ms.giec.ac.cn) |
| Abstract | Kojic dipalmitate(KDP) was synthesized by the way of esterification of palmitic and kojic acids in organic solvent, with double-lipase as the biocatalyst. Four commercially available lipases(Amano PS, Novozym 435, Lipozyme TL IM and Lipozyme RM IM) were used to group six double-lipase combinations. These combinations were studied and Amano PS-Novozym 435 was found to have the best efficiency and was selected for optimizing the reaction conditions. The optimal reaction conditions were as follows. The mass ratio of Amano PS to Novozyme 435 was 1:1.5, with stiffing speed of 500 r/min, substrates molar ratio of 1:2, 50 degrees C, 5%(mass fraction) catalyst dosage of kojic acid quantity and using acetone as co-solvent. Under these conditions, the diesterification of C5 and C7 hydroxyl groups of kojic acid molecule could be well catalyzed by double-lipase and realize a high KDP yield of 85%. |
| Keyword | Kojic acid Palmitic acid Kojic dipalmitate Double-lipase catalysis Diesterification |
| DOI | 10.1007/s40242-017-7048-3 |
| WOS Keyword | ACID ; PRODUCTS |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | Special Funds of Applied Science and Technology Research of Guangdong Province, China[2015B020241002] ; Scientific and Technological Project of Guangdong Province, China[2016A010104008] |
| WOS Research Area | Chemistry |
| Funding Organization | Special Funds of Applied Science and Technology Research of Guangdong Province, China ; Scientific and Technological Project of Guangdong Province, China |
| WOS Subject | Chemistry, Multidisciplinary |
| WOS ID | WOS:000426019100009 |
| Publisher | HIGHER EDUCATION PRESS |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.giec.ac.cn/handle/344007/23538 |
| Collection | 中国科学院广州能源研究所 |
| Corresponding Author | Lu Pengmei |
| Affiliation | Chinese Acad Sci, Key Lab Renewable Energy, Guangzhou Inst Energy Convers, Guangdong Key Lab New & Renewable Energy Res & De, Guangzhou 510640, Guangdong, Peoples R China |
| Recommended Citation GB/T 7714 | Wang Zhiyuan,Luo Wen,Fu Junying,et al. Double-lipase Catalyzed Synthesis of Kojic Dipalmitate in Organic Solvents[J]. CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,2017,33(6):903-907. |
| APA | Wang Zhiyuan,Luo Wen,Fu Junying,Li Zhibing,Wang Zhongming,&Lu Pengmei.(2017).Double-lipase Catalyzed Synthesis of Kojic Dipalmitate in Organic Solvents.CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,33(6),903-907. |
| MLA | Wang Zhiyuan,et al."Double-lipase Catalyzed Synthesis of Kojic Dipalmitate in Organic Solvents".CHEMICAL RESEARCH IN CHINESE UNIVERSITIES 33.6(2017):903-907. |
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